Lanostane Triterpenes from the Fungus Pisolithus tinctorius
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چکیده
Um novo triterpeno, 3β,22ξ,23ξ-triidróxi-22ξ-acetóxi-24-metil-lanosta-8,24(28)-dieno-31-al, denominado pisosteral, e quatro triterpenos lanostanos conhecidos, 3β,22ξ,23ξ-triidróxi-22ξ-acetóxi24-metil-lanosta-8,24(28)-dieno (pisosterol), 3α,22ξ,23ξ-triidróxi-22ξ-acetóxi-24-metil-lanosta8,24(28)-dieno (3-epi-pisosterol), 3β,22ξ,23ξ-triidróxi-23ξ-acetóxi-24-metil-lanosta-8,24(28)-dieno e 3β,22ξ,23ξ-triidróxi-22ξ-acetóxi-24-etil-lanosta-8,24(28)-dieno, foram isolados do corpo de frutificação do fungo Pisolithus tinctorius, coletado em uma plantação de Eucalyptus. De uma linhagem de P. tinctorius isolada de Pinus taeda, foram isolados quatro triterpenos conhecidos derivados do lanostano, 3β,22ξ-diidróxi-24-metil-lanosta-8,24(28)-dieno, 3β,22ξ-diidróxi-24-etillanosta-8,24(28)-dieno, 3β-hidróxi-lanosta-8,24-dieno (lanosterol) and 3β-hidróxi-lanosta-7(8),9,24trieno (agnosterol). Essas substâncias foram identificadas a partir de métodos químicos e físicos, principalmente espectrometria de massas e ressonância magnética nuclear 1D e 2D.
منابع مشابه
Cytotoxic activity of pisosterol, a triterpene isolated from Pisolithus tinctorius (Mich.: Pers.) Coker & Couch, 1928.
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تاریخ انتشار 2005